Flu Mutating

Photo courtesy of the Centers for Disease Control and Prevention

Facts matter: Sign up for the free Mother Jones Daily newsletter. Support our nonprofit reporting. Subscribe to our print magazine.


Barack Obama warned today of a resurgence of flu this autumn. But it’s summer in the northern hemisphere. Hard to fret in warm weather. Right?

Well here are some developments worth the worry, summed up by New Scientist.

In June, more than 98 percent of genotyped flu cases in the US were caused by the pandemic swine flu—which is to be expected, since seasonal flus tend to die out in summer.

But the same high percentages of pandemic flu are appearing in the southern hemisphere, where swine flu, A(H1N1), is replacing the seasonal flu.

In the Australian state of Victoria, swine flu now accounts for 99 percent of all flu cases, with similar numbers from South America. The seasonal vaccine is proving useless.

The pandemics of 1918, 1957, and 1968 also completely replaced their seasonal flus.

Yet many drug companies are still laboring to produce seasonal flu vaccines for use later this year for the northern hemisphere—when they might well prove useless.

It’s also possible that three viruses will be circulating later this year: the milder H1N1, plus H3N2, plus the swine flu A(H1N1). In this complicated scenario, seasonal and pandemic vaccines would be needed with people in different age groups requiring vaccines based on their exposure to past flus.

During previous pandemics, the pandemic virus mutated and its effects worsened. Some ominous signs are emerging now with swine flu, including a mutation to the virus’s polymerase enzyme that allows it to replicate more efficiently. This mutation appeared in Shanghai and could make the virus more contagious or more virulent or both.

Three cases of resistance to the main antiviral drug Tamiflu were discovered last week in Denmark, Japan, and Hong Kong—including one in a girl who had never taken the drug. This suggests that Tamiflu-resistant swine flu might already be circulating.

Plus the news from Germany today that swine flu is capable of spreading from people to pigs and then rapidly between pigs. This was an experimental exposure in Germany. But if swine flu really does get loose in the ghastly world of pig farms, there’s a risk of the virus mixing with other strains to create a real flu monster.

The German researchers were heartened the virus did not spread to five chickens housed with the pigs. That’s the worst case scenario: a swine-avian flu hybrid. The H2N3 seasonal flu currently circulating has the ability to bridge that gap since it’s composed of swine and avian flu genes dating back to the 1957 pandemic.

Enjoy smmer. Winter’s going to get interesting.
 

REAL QUICK, REAL URGENT

Minority rule, corruption, disinformation, attacks on those who dare tell the truth: There is a direct line from what's happening in Russia and Ukraine to what's happening here at home. And that's what MoJo's Monika Bauerlein writes about in "Their Fight Is Our Fight" to unpack the information war we find ourselves in and share a few examples to show why the power of independent, reader-supported journalism is such a threat to authoritarians.

Corrupt leaders the world over can (and will) try to shut down the truth, but when the truth has millions of people on its side, you can't keep it down for good. And there's no more powerful or urgent argument for your support of Mother Jones' journalism right now than that. We need to raise about $450,000 to hit our online fundraising budget in these next few months, so please read more from Monika and pitch in if you can.

payment methods

REAL QUICK, REAL URGENT

Minority rule, corruption, disinformation, attacks on those who dare tell the truth: There is a direct line from what's happening in Russia and Ukraine to what's happening here at home. And that's what MoJo's Monika Bauerlein writes about in "Their Fight Is Our Fight" to unpack the information war we find ourselves in and share a few examples to show why the power of independent, reader-supported journalism is such a threat to authoritarians.

Corrupt leaders the world over can (and will) try to shut down the truth, but when the truth has millions of people on its side, you can't keep it down for good. And there's no more powerful or urgent argument for your support of Mother Jones' journalism right now than that. We need to raise about $450,000 to hit our online fundraising budget in these next few months, so please read more from Monika and pitch in if you can.

payment methods

We Recommend

Latest

Sign up for our free newsletter

Subscribe to the Mother Jones Daily to have our top stories delivered directly to your inbox.

Get our award-winning magazine

Save big on a full year of investigations, ideas, and insights.

Subscribe

Support our journalism

Help Mother Jones' reporters dig deep with a tax-deductible donation.

Donate